Lumonol Review: The Remarkable Power of Noopept By Avanse Nutraceuticals

In the world of nootropics, it’s easy to find products with big marketing and a lack of information available to back it up. What’s in the supplement, and how will it affect my performance, focus, and memory? These are all areas we work hard to get to the bottom of when we test out a new supplement. When we set out to review Lumonol, we didn’t have any trouble finding information from the company behind it.

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Developed and manufactured in the United States by Avanse Nutraceuticals, Lumonol’s site provides a great deal of content on its ingredients and effectiveness, along with a 90 day money back guarantee. We set out to find out if the information and transparency on their site matched up with a quality product. Read below for our full Lumonol review.

Lumonol Ingredients

The Ingredients

Lumonol’s ingredients are grouped into blends focusing on three main goals: Focus, Energy, and Memory.

• Vitamin B12 (Methylcobalamin) – 250mcg
  • An essential vitamin B nutrient, B12 plays an important role in numerous bodily functions, including neurological function and development. The particular form of B12 contained in Lumonol is a form most often used to reduce brain fog and promote mental energy due to its ability to cross the blood-brain barrier.
• Memory Blend – 170mg
  • There are no listed amounts for each individual component of the proprietary blend, but the ingredients are below.
• Alpha GPC
  • Choline is a vital compound in neurotransmission, and research suggests many Americans don’t get enough from their regular diets (in fact, choline-based nootropics are increasingly common, and some of our testers have experienced enhanced memory and focus simply from supplementing choline). It’s a common ingredient in many nootropic stacks, and we’re not surprised Avanse included it in Lumonol. Alpha GPC is one of the most bioavailable forms of choline and among the best compounds at increasing brain concentration of choline after ingestion, we generally think of it as the highest quality form of choline in nootropic supplements.
• Ginkgo Biloba
  • Ginkgo has been used for thousands of years to promote memory in Chinese medicine. More recently, clinical studies and research reviews have pointed to its efficacy in fighting dementia and neural decline.
• Focus Blend – 515mg
  • There are no listed amounts for each individual component of the proprietary blend, but the ingredients are below.
• Noopept
  • This is perhaps Lumonol’s signature ingredient, and it contains 15mg of Noopept. Originally studied for its use in fighting cognitive decline, Noopept is now linked to powerful nootropic effects. Its effect is similar to Piracetam, a long-time preferred ingredient for nootropic/brain supplement pioneers. However, a much lower dosage of Noopept is needed to achieve the same cognitive boost, up to 1000 times less, in fact. Both Noopept and Piracetam have been shown to be well-tolerated by users with a generally low risk of side effects. *As always, it’s a good idea to consult with your doctor before starting a new supplement regime. Noopept metabolizes very quickly, within 25 minutes or less after oral ingestion, and it has a potentially cumulative effect, meaning it gets more effective after repeated use. Our testers felt its effects very quickly after taking Lumonol. Noopept also provides a neuroprotective when supplemented, potentially protecting against oxidative damage/stress and some physical traumas. This class of compounds interacts with choline receptors, and we’re glad to see Lumonol include citicoline in the supplement as well; taking Piracetam or similar compounds without enough choline can in some cases result in a dull headache, though none of our testers experienced this at any point with Lumonol.
• Acetyl L-Carnitine
  • This compound pairs very well with choline; when combined, the two form the neurotransmitter acetylcholine. Having both in the same supplement is a good hedge in case the body is deficient in either compound. We’re pleased Lumonol includes both compounds in order to promote acetylcholine levels.
• L-Tyrosine
  • Avanse claims L-Tyrosine pairs well with many other ingredients in Lumonol’s nootropic stack. There’s good evidence to support that claim, as L-Tyrosine is well-linked to improving cognitive performance under conditions of stress, and the compound has been shown to actually reduce symptoms of stress itself, likely because it is involved in the production of dopamine.
• Phosphatidylserine
  • This is a widely-used nootropic compound that, until the 1990s, was very difficult to synthesize. Clinical testing and trials have linked it to improved cognition, and the compound has also been shown to reduce cortisol (a well-known stress hormone) levels.
• Energy Blend – 430mg
  • There are no listed amounts for each individual component of the proprietary blend, but the ingredients are below.
• Guarana
  • Guarana is a climbing Amazonian plant containing almost four times the amount of caffeine as coffee beans. Even in low doses, it can provide more stimulation than caffeine alone due to its concentration of phytonutrients. Guarana pairs especially well with many of the nootropic compounds found in Lumonol, increasing their effectiveness and pronounced effects across the board.
• Panax Ginseng
  • Like its counterpart ginkgo, ginseng has been used for millennia to improve memory. Ginseng is especially well-tied to memory response time, decreasing the amount of time it takes to recall facts.
• Hordenine
  • This is a compound we haven’t seen in too many product before, but due to Lumonol’s inclusion of other dopamine-enhancing ingredients (see L-Tyrosine, above), we’re not surprised. Hordenine increases dopamine availability by inhibiting its breakdown (or oxidation) in our bodies. It’s a good complement to L-Tyrosine in this particular supplement, another one of Lumonol’s synergistic interactions.
• Other Ingredients: Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Usage Guidelines

From the Avanse packaging and website:

For mental performance, focus and energy: Start with 2 capsules per day. Lumonol’s effects are cumulative, building over time. With that said, Lumonol does provide an intense boost to motivation within 20 minutes of ingestion. We recommend that if you are new to nootropics that upon receiving your Lumonol order you run a sensitivity test by consuming a single capsule per day for the first few days.

Serving Size: Upon successful completion of a 1 capsule “tolerance test day”, take 2 capsules per day. You may take Lumonol before eating, or after, and may consume after lunchtime if a productive afternoon is required. Taking Lumonol too close to bedtime may result in a restless night. Lumonol should be supplemented in 90 day cycles, with 15 – 30 days break in between. Lumonol’s effects build with time.

We had BrainWiz testers take between 1 and 2 capsules per day.