DMAE – Brain Wiz https://brainwiz.org Level-up your mind! Thu, 09 Feb 2017 22:24:25 +0000 en-US hourly 1 https://wordpress.org/?v=6.4.3 What Is Magnesium L-Threonate (and Which Brain Magnesium Is Best)? https://brainwiz.org/research-reports/magnesium-l-threonate-brain/ https://brainwiz.org/research-reports/magnesium-l-threonate-brain/#respond Tue, 16 Feb 2016 23:54:52 +0000 http://brainwiz.org/?p=1108 Magnesium is an essential element in the body, and it’s a nutrient many Americans are deficient in. In fact, magnesium deficiency is the second most common deficiency in Western society behind vitamin D. Magnesium plays crucial roles in sleep, cognition, memory, and muscle health, and it’s an ingredient we’ve seen in numerous nootropics. One of […]

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Magnesium is an essential element in the body, and it’s a nutrient many Americans are deficient in. In fact, magnesium deficiency is the second most common deficiency in Western society behind vitamin D. Magnesium plays crucial roles in sleep, cognition, memory, and muscle health, and it’s an ingredient we’ve seen in numerous nootropics. One of these is Magtein, a trademarked and proprietary magnesium compound also referred to as magnesium l-threonate.

What is Magnesium L-Threonate

Thinking about trying magnesium? Read about our favorite magnesium brain supplement here.

However, the type of magnesium in these supplements varies significantly. Many of the oldest and most established magnesium supplements are made up of magnesium citrate or magnesium oxide. However, these compounds aren’t always the most efficient for biological processes, and many have difficulty increasing magnesium concentrations in the brain.

Recently, researchers have developed a new magnesium compound that appears more efficient at crossing the blood-brain barrier, and it’s a form of magnesium we’re seeing in some of our favorite supplements, including MagTech. Trademarked as Magtein, magnesium l-threonate has several studies linking it to enhanced memory and brain function. It may even help certain individuals overcome fear-based memories and triggers.

Best Magnesium Brain Supplement

Magtein actually contains less elemental magnesium per dose compared to many other magnesium compounds. Magnesium l-threonate contains magnesium in a form paired with a metabolite of vitamin C. It’s this unique molecular structure that allows the magnesium to more easily cross the blood-brain barrier, increasing free magnesium concentrations in the brain more effectively than other forms.

It’s worth noting that research into magnesium l-threonate is still relatively new, and things like optimal dosage may not yet be known for every user. If you think you may have a mineral deficiency that’s impacting your health, it’s best to speak to a healthcare professional.

For our testers, MagTech, which combines magnesium l-threonate with magnesium glycinate and magnesium taurate, has been their favorite magnesium-focused brain supplement; many also experienced better sleep while taking MagTech. MagTech also forms a base for one of our favorite nootropic stacks for productivity.

We’ll continue testing and reviewing magnesium-based nootropics and supplements as new ones, and potentially new magnesium compounds, come onto the market.

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A Mild Nootropic to Fight Anxiety? Reviewing Neuro Clarity by Nutrition Essentials https://brainwiz.org/supplement-reviews/neuro-clarity-nutrition-essentials/ https://brainwiz.org/supplement-reviews/neuro-clarity-nutrition-essentials/#respond Sat, 19 Dec 2015 00:09:35 +0000 http://brainwiz.org/?p=719 Neuro Clarity (click for best price) by Nutrition Essentials is a bestseller on Amazon when it comes to St. John’s Wort Herbal Supplements, an ingredient we’ve really only seen highlighted in one other nootropic stack, and in very small quantities. Read on to find out how a stack with this herbal primary ingredient fares as a […]

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Neuro Clarity (click for best price) by Nutrition Essentials is a bestseller on Amazon when it comes to St. John’s Wort Herbal Supplements, an ingredient we’ve really only seen highlighted in one other nootropic stack, and in very small quantities. Read on to find out how a stack with this herbal primary ingredient fares as a nootropic.

Neuro Clarity Nutrition Label and Ingredients

Neuro Clarity Nutrition Label and Ingredients

The Ingredients

  • St. John’s Wort (as 3% extract) – 250 mg
    • St. John’s Wort has been used to treat depression and other mood disorders, and as a neuroprotective agent.
  • Glutamine (as L-glutamine hydrochloride) – 150 mg
    • This is one of the body’s most abundant amino acids, and we normally see glutamine supplementation for bodybuilders and athletes. It’s been linked to increased muscular endurance, especially in vegetarians or people with low-protein diets.
  • Phosphatidylserine Complex – 125 mg
    • Phosphatidylserine is a phospholipid required to maintain healthy nerve cell membranes. It supports cognitive function and the ability to learn and recall new information.
  • Bacopa Monnieri (20% bacosides) – 100 mg
    • Bacopa Monnieri is an herb used in Ayurveda as an antidepressant and a cognitive booster. While performing stressful cognitive tests, those taking Bacopa Monnieri experienced the herb’s nootropic effects, and reduced stress and cortisol levels. This is a relatively low concentration and low dosage, compared to other supplements we have tested.
  • Acetyl L-Carnitine – 50 mg
    • This compound pairs very well with choline; when combined, the two form the neurotransmitter acetylcholine. Since this supplement does not contain any choline, we suggest that you increase your intake of choline-containing foods, such as eggs, in case the body is deficient in either compound.
  • DMAE Bitartrate – 50 mg
    • DMAE Bitrate, or Deanol,  is a chemical used to treat ADHD, improve memory and boost cognitive function. Deanol is essential to the production of choline, one of the building blocks of the neurotransmitter acetylcholine, which is vital for a number of nervous system activities, including signaling the heart to keep beating.
  • Ginkgo Biloba (as 24% extract) – 50 mg
    • Ginkgo has been used for thousands of years to promote memory in Chinese medicine. More recently, clinical studies and research reviews have pointed to its efficacy in fighting dementia and neural decline.
  • Vinpocetine – 2 mg
    • Vinpocetine is a chemical derived from the periwinkle plant, and known to increase cerebral blood flow. Doctors in Hungary have been prescribing this compound to treat cerebrovascular disorders for decades.
  • Other Ingredients: Gelatin, Magnesium Stearate, and Dicalcium Phosphate.

Usage Guidelines

Serving Size: 1 capsule

Neuro Clarity Review

What Our Testers Say

“I took this during a high-stress week at my job. Since there were no real directions on the bottle, I just took it in the mornings, along with my coffee. I felt like it evened me out a bit, as far as anxiety and stress and anxiety go, but I’m not sure it had any effect on my cognition.”

“While I didn’t really feel any sharper or more focused while on Neuro Clarity, I did feel like it helped me deal with day-to-day anxiety. I will keep this around to help me deal with craziness at work.”

“I tried this out for a couple of weeks, usually taking it first thing in the morning on an empty stomach. I still had my usual trouble with a little brain fog in the morning, but I did notice that situations that usually stressed me out at work, were a little easier to handle while on Neuro Clarity.”

“This is one of those supplements that are a tad too mild for me, but I can see it maybe being good for folks who are sensitive to caffeine, or prone to anxiety.”

Neuro Clarity
3.4 / 5 Score
Pros
  • Stimulant free
  • Straightforward stack
  • Cons
  • No choline source
  • Summary
    Neuro Clarity is an entry-level, straightforward stack, but we wish it included a high-quality choline source.
    Focus
    Energy
    Memory
    Beginner Friendly

    BrainWiz Tips

    • Our testers all experienced mild effects with no jitters. This could be a good start if you’re new to the world of nootropics and want to explore brain enhancers gradually.
    • This supplement seems to pair well with coffee and other food/drink sources of caffeine (our testers didn’t try it with other caffeine-containing nootropics, which could potentially cause jitteriness).
    • Take with choline-containing foods, like eggs and meat, to take advantage of the choline-friendly ingredients in this stack.
    • St. John’s Wort is known to interact with a number of medications and, as with any supplement, it is a good idea to check with your doctor or medical practitioner before use.

    Supplement Summary

    While not the strongest supplement out there, Neuro Clarity may be a solid option for those looking for a caffeine-free, entry level stack. Our testers all experienced a sense of well-being while taking the supplement, but little observational cognitive boost.

    Neuro Clarity was mildly effective for some of our testers dealing with high-stress and high-anxiety situations.

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    Energy That Comes Up Short? Reviewing Focus+ by Excelerol https://brainwiz.org/supplement-reviews/excelerol-focus-plus/ https://brainwiz.org/supplement-reviews/excelerol-focus-plus/#respond Sat, 12 Dec 2015 15:31:58 +0000 http://brainwiz.org/?p=658 We’ve learned to be skeptical of any product claiming to be “The #1” at pretty much anything. Focus + by Excelerol (click for best price) is a liquid capsule nootropic stack, and the company’s original formula claims to America’s number #1 brain supplement (we’ve heard that before). The list of ingredients in their newer Focus+ stack, is […]

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    We’ve learned to be skeptical of any product claiming to be “The #1” at pretty much anything. Focus + by Excelerol (click for best price) is a liquid capsule nootropic stack, and the company’s original formula claims to America’s number #1 brain supplement (we’ve heard that before).

    The list of ingredients in their newer Focus+ stack, is quite familiar, featuring a significant number of well-researched nootropics, paired with an unknown (but observationally high) dose of stimulants and adaptogens. Read on to find out what our testers thought about it, and whether or not Focus+ is on par with the best nootropics.

    Excelerol Focus Plus Label and Indgredients

    Excelerol Focus Plus Label and Indgredients

    The Ingredients

    Vitamin B12 – 1,250

    An essential vitamin B nutrient, B12 plays an important role in numerous bodily functions, including neurological function and development.

    Niacin – 5 mg

    This is a common B vitamin linked to both increased cognition and longevity, and niacin is responsible for the famous (and harmless) “flush” some users get when taking it.

    Huperzine 1% Standardized – 12.5 mcg

    Huperzine A is a compound derived from Chinese club moss that has been used to improve cognitive performance in patients with Alzheimer’s and vascular dementia.

    Vinpocetine – 600 mcg

    Vinpocetine is a chemical derived from the periwinkle plant, and it’s known to increase cerebral blood flow. Doctors in Hungary have been prescribing this compound to treat cerebrovascular disorders for decades.

    Proprietary Formulation – 650 mg

    Guarana Extract

    Guarana is a climbing plant native to the Amazon with seeds that contain almost four times the amount of caffeine as coffee. Even in low doses, it often provides more stimulation than caffeine alone  due to its concentration of phytonutrients.

    Kola Nut Extract

    The fruit of the kola tree, the kola nut has been used as a flavoring ingredient in many consumer products. It contains both caffeine and theobromine, an alkaloid also found in the cacao plant.

    DMAE

    DMAE Bitrate, or Deanol, is a chemical used to treat ADHD, improve memory, and boost cognitive function. Deanol is essential to the production and of choline, one of the building blocks of the neurotransmitter acetylcholine. It’s a chemical precursor to choline and boosts alertness.

    Acetyl L-Carnitine

    This compound pairs very well with choline; when combined, the two form the neurotransmitter acetylcholine. Having both in the same supplement is a good hedge in case the body is deficient in either compound.

    Bacopa Monnieri Extract

    Bacopa Monnieri is an herb used as an antidepressant and a cognitive booster. While performing stressful cognitive tests, subjects taking Bacopa Monnieri experienced the herb’s nootropic effects and reduced both stress and cortisol levels.

    Peppermint Oil

    Often used as a flavoring agent, peppermint oil has also been used in the treatment of a variety of digestive problems. The smell of peppermint has been shown to enhance memory.

    Tulsi (Holy Basil) Extract

    A noted adaptogen, ursolic acid (the active ingredient in this extract) helps reduce the negative effects of stress. Note: In high dosages, research indicates ursolic acid may actually be an anti-fertility agent and could reduce reproductive capability in the short term. We’ve had good experience with adaptogens before, but wonder if it would have been a good idea to leave this ingredient out, given its potential side effects.

    Ginkgo Biloba Extract

    Ginko has been used in Chinese medicine  for thousands of years to promote memory. More recently, clinical studies and research reviews have pointed to its efficacy in fighting dementia and neural decline.

    Rhodiola Extract

    While there’s some evidence that Rhodiola Rosea can combat the effects of physical stress, it’s best known and well-researched to fight fatigue from mental challenges and tasks. Basically, evidence suggests this herb helps us better manage stress, and it also combats fatigue we might feel from mentally (and potentially physically) grueling tasks. Some early research also indicates Rhodiola could improve overall longevity and brain health  in mammals.

    Phosphatidylserine

    This is a widely-used nootropic compound that, until the 1990s, was very difficult to synthesize. Clinical testing and trials have linked it to improved cognition, and the compound has also been shown to reduce levels of cortisol (a well-known stress hormone).

    L-Tyrosine

    L-Tyrosine is linked to improving cognitive performance under conditions of stress, and the compound has been shown to actually reduce symptoms of stress itself, likely because it is involved in the production of dopamine.

    Green Tea Extract, White Tea Extract, Black Tea Extract

    All three of these teas contain varying quantities of polyphenols, caffeine, and l-theanine. An amino acid that’s becoming an increasingly common ingredient in nootropics, l-theanine promotes relaxation without being a sedative. Research suggests it also helps the brain deal with stress. Often paired with caffeine, l-theanine effects appear complementary to the world’s most popular stimulant. It may also increase brain activity and memory.

    Alpha Glycerylphosphorylcholine (Alpha-GPC)

    Choline is a vital compound in neurotransmission, and research suggests many Americans don’t get enough from their regular diets. (In fact, choline-based nootropics are increasingly common, and some of our testers have experienced enhanced memory and focus simply from supplementing choline.) This is the same form of choline as in popular stack (and BrainWiz tester favorite) Alpha Brain.

    Citicoline

    Choline is a vital compound in neurotransmission, and research suggests many Americans don’t get enough from their regular diets. (Choline-based nootropics are increasingly common, and some of our testers have experienced enhanced memory and focus simply from supplementing choline.) It’s a common ingredient in many nootropic stacks.

    Other Ingredients: Glycerin, Hypromellose (Vegetarian), Titanium Dioxide, FD&C Blue #1, FD&C Yellow.

    Focus+
    1.9 / 5 Score
    Pros
  • Quick hit of energy
  • Some popular ingredients
  • Cons
  • Noticeable crash
  • Mystery dosages
  • Overstimulating
  • Summary
    Focus+ by Excelerol made most of our testers uncomfortable with a quick wave of jittery energy, which made focusing on the task at hand harder than without any supplements.
    Focus
    Energy
    Memory
    Beginner Friendly

    Excelerol Focus Plus Review

    Usage Guidelines

    Take 1 capsule daily with plenty of water.

    What Our Testers Say

    “I was excited to try this, since I had such a great experience with with the guarana in Lumonol.  Unfortunately, this wasn’t the case with Focus+.  I took 1 capsule, with breakfast, and two full glasses of water, but that was still not enough to deter the jitters. I felt a ton of nervous energy, and actually had a harder time concentrating than usual. This feeling lasted for about 4 hours, when I crashed hard.”

    “I wasn’t too excited to try this product, especially because they did not have specifics on how much Holy Basil, or at what concentration, the ”˜Proprietary Formulation contained.’ I also didn’t know whether or not that formulation contained enough of an ingredient, say, Rhodiola, to meet the minimal effective dose. I tested it, though I was also hesitant because Ursolic Acid has some potential side effects. I took it in the morning, with with a shake, and felt a definite rush of energy. This was as effective as my pre-workout for energy, but I didn’t get much more out of it.”

    “I felt a tad on edge on this supplement, whether I took it with or without coffee. There were no real cognitive benefits while taking this either.”

    “As I have mentioned before, I do my best to avoid artificial coloring. I understand that this is part of their branding, each individual pill is blue and green with each capsule individually labeled, but I believe that a product can be just as recognizable for its quality as it is for its branding.  I do like this product as an energy supplement, but don’t think I would consider adding it to my permanent rotation even if Excelerol removed their overkill, on-pill branding. I prefer to get my jolt from coffee.”

    BrainWiz Tips

    • This stack contains several stimulant ingredients, loaded with caffeine. We suggest you take this supplement with food, and away from other caffeine-containing beverages, like coffee or tea.
    • Make sure to drink plenty of water throughout the day, as this supplement can dehydrate you.
    • Adaptogens like Rhodiola Rosea and Panax Ginseng may actually boost the effects of common stimulants like caffeine.
    • As with any supplement or nutritional regimen, you should talk to your doctor or medical professional before use.
    • The bottle suggests taking this supplement up to 3 times a day, but beware of taking it too late into the afternoon, especially if you have trouble falling asleep.

    Supplement Summary

    Focus+ may be a good alternative for non-coffee drinkers looking for a buzz, but for our testers, the benefits stopped there. Despite having an impressive list of ingredients, the fact that neither the quantities nor concentration of many ingredients listed makes us doubt there’s enough of them in the stack to really make a difference.

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    The Ideal Stimulant-Free Stack? Reviewing CogniYouth https://brainwiz.org/supplement-reviews/cogniyouth/ https://brainwiz.org/supplement-reviews/cogniyouth/#respond Mon, 23 Nov 2015 02:46:22 +0000 http://brainwiz.org/?p=521 The majority of the nootropics we review have some overlap in ingredients, and the differences often lie in synergistic (or for the ones that don’t seem to work, seemingly random) combinations, precise dosages, and delivery mechanisms. When we first heard about CogniYouth, we tried to guess some of the ingredients before looking at the label, […]

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    The majority of the nootropics we review have some overlap in ingredients, and the differences often lie in synergistic (or for the ones that don’t seem to work, seemingly random) combinations, precise dosages, and delivery mechanisms. When we first heard about CogniYouth, we tried to guess some of the ingredients before looking at the label, based solely off the manufacturer’s claims.

    Suffice it to say, we were surprised. What surprised us most about CogniYouth is what it opted to leave out, namely stimulatory ingredients such as caffeine and guarana. What it does have is a list of ten of the most trusted natural nootropic ingredients in dosages around where we like to see each fall.

    Another thing that stood out? The doctor-approved certificate right on their site, along with the name and opinion of an actual M.D. (click on the button in the bottom right). CogniYouth calls itself the “ultimate brain vitamin,” and with seemingly quality ingredients prioritized over the quick buzz of stimulants and “proprietary blends,” we were excited to see if it worked. Read below to see our take.

    CogniYouth Label

    CogniYouth Label

    The Ingredients

    Vitamin B6, 5 mg and Vitamin B12, 20 mcg

    Two important B vitamin complexes linked to reduced fatigue and mental performance. Some of the most common nootropic ingredients we see that work synergistically in brain boosting blends.

    Bacopa monnieri extract, 300 mg

    Bacopa Monnieri is an herb used as an antidepressant and a cognitive booster. While performing stressful cognitive tests, subjects taking Bacopa Monnieri experienced the herb’s nootropic effects and reduced both stress and cortisol levels.

    Choline Bitartrate, 200 mg

    Choline-Bitartrate is a vitamin-like chemical thought to help enhance levels of acetylcholine. Choline is an essential nutrient vital for brain function.

    Rhodiola rosea (standardized to 3% Rosavins), 200 mg

    While there’s some evidence that Rhodiola Rosea can combat the effects of physical stress, it’s best known and well-researched to fight fatigue from mental challenges and tasks. Basically, evidence suggests this herb helps us better manage stress, and it also combats fatigue we might feel from mentally (and potentially physically) grueling tasks. Some early research also indicates Rhodiola could improve overall longevity and brain help in mammals.

    Acetyl-L-Carnitine HCL, 200 mg

    This compound pairs very well with choline; when combined, the two form the neurotransmitter acetylcholine. Having both in the same supplement is a good hedge in case the body is deficient in either compound.

    Ginkgo Biloba, 120 mg

    Ginkgo has been used in Chinese medicine for thousands of years to promote memory. More recently, clinical studies and research reviews have pointed to its efficacy in fighting dementia and neural decline.

    Soybean extract (phosphatidylserine), 100 mg

    Phosphatidylserine is a phospholipid required to maintain healthy nerve cell membranes. It supports cognitive function and the ability to learn and recall new information.

    DMAE Bitartrate, 50 mg

    Also known as Deanol, DMAE is a chemical used to improve memory and boost brain function.  It’s especially important in the production of choline (see Choline-Bitartrate, below), one of the building blocks of acetylcholine, vital for nervous system function.

    Huperzine A, 50 mcg

    Huperzine A is a compound usually derived from Chinese club moss that has been used to improve cognitive performance in patients with declining mental health.

    Other ingredients: Gelatin, rice flour, silica, magnesium stearate, and titanium dioxide.

    Usage Guidelines

    We recommend taking 2 capsules in the morning with food, daily. CogniYouth was carefully designed as a daily “Brain Vitamin” with the intention of aiding in overall brain health, memory, concentration, energy and well-being while battling the effects of age-related cognitive decline.

    CogniYouth will be effective and safe to take continuously provided you stick to recommended dosages. If you are on prescribed medication, consult with your doctor or prescribing health care practitioner about taking CogniYouth while on medication.

    CogniYouth
    3.7 / 5 Score
    Pros
  • Stimulant free
  • Adaptogenic blend
  • Beginner friendly
  • Broad stack
  • Cons
  • Not quick energy
  • Summary
    For our reviewers, CogniYouth is a beginner-friendly stack filled with stress-fighting adaptogens, though it lacks stimulants, caffeine, or ingredients that gave us a "quick" energy boost. For some folks, that's preferable.
    Focus
    Energy
    Memory
    Beginner Friendly

    What Our Testers Say

    “I’m a fan of Rhodiola rosea as an adaptogen [fights the physical effects of stress], and I was glad to see it paired with ingredients that compliment its properties. CogniYouth doesn’t have caffeine or stimulants, though I did experience a bit of an energy boost from the B vitamins, and the adaptogens on the ingredient list were helpful in fighting off mid-day fatigue (I fall victim to the 2pm lull pretty easily). This isn’t a turbo-charged nootropic stack, and it won’t turn you into the guy from Limitless, but for something touted as a ”˜brain vitamin,’ I could definitely see myself taking it most mornings.”

    “CogniYouth wasn’t super fast acting, and the manufacturer suggests its impact builds over time. I didn’t feel a crazy boost, but it was at least on par with what I normally feel taking Rhodiola or bacopa on their own or in combo. If I’m approaching a tight deadline and need to supercharge my mind, it wouldn’t be what I reached for. But that’s not really the point, and it may be a solid entry point for people looking to try out a nootropic.”

    “I really appreciated that this didn’t have caffeine in it, as I’ve been trying to carefully watch my intake of stimulants, I think a lot of people ignore how powerful even caffeine can be. So I was pleased to see some of my favorite ingredients in a caffeine-free stack, which is something we’ve been hoping for from some other companies for awhile.”

    “The focus I felt from CogniYouth was mild. But I don’t think it’s right to treat this like some of the other nootropic stacks we’ve tested, it’s meant more for brain health and effects that build over time, not the fast-metabolizing energy I like from some other stacks.”

    BrainWiz Tips

    • Take with food in the morning to optimize supplement digestion and minimize the risk of an upset stomach.
    • CogniYouth is caffeine free, though several of our testers enjoyed taking it with coffee in the morning.

    Supplement Summary

    CogniYouth didn’t blow us away with a rapid burst of energy or a proprietary ingredient stack. But its effects were consistent, and it may just be the stimulant-free stack a few of our testers have been looking for.

    If you’re new to nootropics or want to reduce your use of caffeine, this is one of our current top choices with ingredients we come back to time and time again.

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    Do You Want A Mild Brain Boost? Reviewing Ginkgo Smart By Irwin Naturals https://brainwiz.org/supplement-reviews/ginkgo-smart-irwin-naturals/ https://brainwiz.org/supplement-reviews/ginkgo-smart-irwin-naturals/#respond Thu, 10 Sep 2015 21:59:17 +0000 http://brainwiz.org/?p=169 Irwin Naturals is one of the more recognizable supplement companies in the United States. While they’re primarily known for things like natural sleep aids and vitamins, they also produce several supplements designed to produce brainpower. These are generally entry-level nootropics, meaning they’re mostly blends of well-established, if not especially cutting edge or proprietary, ingredients. We wanted […]

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    Irwin Naturals is one of the more recognizable supplement companies in the United States. While they’re primarily known for things like natural sleep aids and vitamins, they also produce several supplements designed to produce brainpower. These are generally entry-level nootropics, meaning they’re mostly blends of well-established, if not especially cutting edge or proprietary, ingredients.

    We wanted to find out if they packed any punch, or if their nootropics were just souped-up vitamin duds. The first up for review is Ginkgo Smart by Irwin Naturals (click for best price). Let’s take a look inside.

    Ginkgo Smart Label

    Ginkgo Smart Label & Ingredients

    The Ingredients

    • Fish Oil (30% Omega-3 Fatty Acids) – 878 mg
      • Omega-3 fatty acids play crucial roles in many bodily functions, and while they’re often recommended for heart health, it’s important not to overlook their benefit to the brain. These fatty acids are heavily concentrated in the brain and are important to its development and function. Many Americans (and generally people in Western countries) don’t get enough omega-3 fatty acids in their diet. This isn’t a particularly high concentration of omega-3s, and we’ve seen supplements with up to 80% purity instead of the 30% here. Of course, it’s just one ingredient in this supplement, but more and more companies are creating fatty acid blends targeted for brain health, be on the lookout for our reviews of those soon.
    • Ginkgo powder (leaf) – 400mg/Ginkgo extract (24% flavone glycodises, 6% terpene lactones) (leaf) – 120 mg
      • Ginkgo has been used for thousands of years to promote memory in Chinese medicine. More recently, clinical studies and research reviews have pointed to its efficacy in fighting dementia and neural decline.
    • Acetyl L-Caritine – 50 mg
      • This compound pairs very well with choline; when combined, the two form the neurotransmitter acetylcholine. Having both in the same supplement is a good hedge in case the body is deficient in either compound. We’re pleased Lumonol includes both compounds in order to promote acetylcholine levels.
    • Choline (as Choline-Bitartrate) – 50 mg
      • Choline-Bitartrate, a vitamin-like chemical, helps the body produce acetylcholine, one of the main neurotransmitters involved in learning along with other cognitive processes. It’s a fairly common ingredient in nootropic supplements and stacks. Many Americans are choline deficient, and this dosage is a bit more than 100% of the recommended daily value.
    • DMAE Bitartrate – 50 mg
      • DMAE Bitrate, or Deanol, is a chemical used to treat ADHD, improve memory and boost cognitive function. Deanol is essential to the production of choline, one of the building blocks of the neurotransmitter acetylcholine, which is vital for a number of nervous system activities, including signaling the heart to keep beating.
    • Trimethylglycine – 50 mg
      • Also known as betaine, may act similarly to choline when ingested, though its most documented benefits are actually in the realm of physical performance (reduced fatigue, increased muscular endurance). This is a compound we don’t see too much of in the world of nootropics, mostly because so much of the research evidence surrounding it has to do with muscular endurance rather than brain enhancement.
    • Alpha-Lipoic Acid 20 mg
    • Velvet Bean extract (10% L-dopa) 10 mg
      • Velvet bean extract is a solid, concentrated source of L-DOPA, a drug commonly used to treat Parkinsons Disease. It is a dopamine precursor.
    • Vinpocetine (from Lesser Periwinkle extract) (whole plant) – 2 mg
      • Vinpocetine is a chemical derived from the periwinkle plant, known to increase cerebral blood flow. Doctors in Hungary have been prescribing this compound to treat cerebrovascular disorders for decades.
    • Toothed Clubmoss extract (1% huperzine A) (plant) – 1 mg
      • Clubmoss is the most common source for Huperzine A, a compound that has been used to improve cognitive performance in patients with Alzheimer’s.
    • BioPerine Complex (BioPerine Black Pepper extract 95% piperine and ginger extract 5% ginerols) – 6 mg
      • BioPerine is a common ingredient in Irwin Naturals products, as well as products from other general supplement manufacturers. Research suggests BioPerine/black pepper extract in the form of piperine helps the body more efficiently absorb a variety of nutrients through the digestive tract. If effective, it’s a good compliment to this supplement’s stack of nootropic ingredients.
    • Other Ingredients: Gelatin, soy lecithin, purified water, glycerin, beeswax, lurmeric, titanium dioxide and sodium copper chlorophyllin. Contains: Soy, Fish (anchovy, sardine)

    Usage Guidelines

    Take two liquid soft gels daily with a full glass of water. Do not use if you may become pregnant, are pregnant or nursing. State of California Prop 65: This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. We had our BrainWiz testers take 2 capsules per day.

    Ginkgo Smart
    3.3 / 5 Score
    Pros
  • Doubles as fish oil
  • Mild boost
  • Cons
  • Caused cramps
  • Summary
    Ginkgo Smart is a very mild nootropic formula with omega-3 included, but some of our testers experienced stomach cramps when taking it.
    Focus
    Energy
    Memory
    Beginner Friendly

    What Our Testers Say

    “I was not expecting to like this supplement; it didn’t contain anything on the label that struck me as particularly effective or innovative. But I have to admit I felt clear-headed every morning I took this (usually with caffeine, but once without; still clear). I’m wondering if the BioPerine helps speed or facilitate absorption, because the effect, though not the most powerful I’ve felt by a long shot, came on pretty quickly.”

    “I made the mistake of taking this on a completely empty stomach the first day, no water, no food, and it caused some very mild nausea. This didn’t happen when I actually followed the instructions and drank it with a big glass of water. If anything, I felt slightly increased focus, but it wasn’t particularly powerful.”

    “I’m actually still taking this supplement. I think I respond well to something a bit milder occasionally, though the entire time I’ve been taking this has been pretty quiet at work. When a bit stressful project comes up, I’ll probably reach for something more powerful. I might swap out with another Irwin Naturals stack for regular use to try it out.”

    “This is probably the mildest supplement I’ve tried that increased focus and energy (I’ve tried others that did nothing, but I’m not counting those). I’d like it if they released a version without the fish oil since I already take a more concentrated fish oil I really like. It’d also be nice if they used non-soy capsules, but that’s a pretty minor concern for me.”

    BrainWiz Tips

    • Our testers all experienced mild effects with no jitters. This is a good start if you’re new to the world of nootropics and want to explore brain enhancers gradually.
    • Take with a full glass of water and/or meal to avoid any stomach cramps; this is often true of fish oil-containing supplements.
    • This supplement seems to pair well with coffee and other food/drink sources of caffeine (our testers didn’t try it with other caffeine-containing nootropics, which could potentially cause jitteriness).
    • If you shouldn’t be taking fish oil for any health reason, it’s a good idea to steer clear of Ginkgo Smart. As with any supplement regime, it’s a good idea to talk to your healthcare provider before making any changes.

    Supplement Summary 

    Ginkgo Smart is a mild brain enhancer good for people who aren’t sure whether nootropics are right for them. It effects are noticeable and very quick, but they won’t bring on Limitless-like focus and new realms of mental clarity. It also doubles as a fish oil supplement, and we appreciate the inclusion of BioPerine as a compound that could potentially enhance absorption of its other ingredients. If you want a mild cognitive boost to pair with breakfast, this is a very solid choice.

    The post Do You Want A Mild Brain Boost? Reviewing Ginkgo Smart By Irwin Naturals appeared first on Brain Wiz.

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    Insurance For Your Brain? Reviewing Choline Force By Bulletproof https://brainwiz.org/supplement-reviews/choline-force-bulletproof/ https://brainwiz.org/supplement-reviews/choline-force-bulletproof/#comments Sat, 05 Sep 2015 10:32:13 +0000 http://brainwiz.org/?p=143 Upgraded Self (also known as Bulletproof) is the producer of high-quality, well-sourced products to boost human performance. Known for Bulletproof Coffee (a mix of coffee, medium chain triglyceride oil, and grass-fed butter, which in conjunction can serve as their own nootropic), Bulletproof produces a number of other brain-boosting supplements. Their best-known nootropic is Unfair Advantage (read our review […]

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    Upgraded Self (also known as Bulletproof) is the producer of high-quality, well-sourced products to boost human performance. Known for Bulletproof Coffee (a mix of coffee, medium chain triglyceride oil, and grass-fed butter, which in conjunction can serve as their own nootropic), Bulletproof produces a number of other brain-boosting supplements. Their best-known nootropic is Unfair Advantage (read our review of Unfair Advantage here), but they also make Choline Force, GABAwave, and Glutathione Force.

    Today, we’re reviewing Choline Force, a blend of powerful brain and energy-promoting compounds. Many people are deficient in the compounds vital to healthy brain function and do not get enough of them from their regular diets; in addition to a blend of nootropic compounds, Choline Force provides an extra dosage of several compounds necessary for neurotransmitter function. This is especially relevant for vegetarians or vegans, as many common sources of choline and other brain-boosting compounds are eggs, meat, and dairy.

    Choline Force Label

    Choline Force Label & Ingredients

    The Ingredients

    Choline Force comes in capsules, with 120 capsules per bottle. There are 30 four-capsule servings per container.

    Active Ingredients:

    One thing we like about Upgraded Self products is that they normally list the amounts of ingredients in each supplement, while many other nootropic companies don’t reveal the dosages in their proprietary blends. With Choline Force that’s especially important, as this supplement works in part by fixing deficiencies in compounds vital to brain function.

    • Choline  (as choline bitartrate) – 500mg
      • Choline-Bitartrate, a vitamin-like chemical, helps the body produce acetylcholine, one of the main neurotransmitters involved in learning along with other cognitive processes. It’s a fairly common ingredient in nootropic supplements and stacks, and Choline Force provides a pretty high dosage compared to other supplements we’ve tried. Many Americans are choline deficient, and the dosage in Choline Force is a bit more than 100% of the recommended daily value for the average adult.
    • Huperzine-A (Lycopodium serrata whole plant extract) – 52 mcg
      • Huperzine A is a compound derived from Chinese club moss that has been used to improve cognitive performance in patients with declining mental health.
    • Vinpocetine – 20mg
      • Vinpocetine is a chemical derived from the periwinkle plant, known to increase cerebral blood flow. Doctors in Hungary have been prescribing this compound to treat cerebrovascular disorders for decades.
    • DMAE (dimethylamineoethanol bitartrate) – 252mg
      • DMAE Bitrate or Deanol,  is a chemical used to treat ADHD, improve memory, and boost cognitive function. Deanol is essential to the production and of choline, one of the building blocks of the neurotransmitter acetylcholine. It’s a chemical precursor to choline and boosts alertness.
    • Vitamin B12 (methylcobalamin) – 100mcg
    • Pantothenic Acid (calcium pantothenate) – 124mg
      • Also known as vitamin B5, this is a water-soluble essential vitamin needed for healthy nervous system function.
    • Pyroglutamic Acid – 252mg
      • Pyroglutamic Acid is an amino acid and a known cognition-enhancing agent that works in conjunction with acetylcholine, GABA, and glycine. We’re happy to see this in a choline-based supplement, as it can enhance its effects. Compared to other supplements with choline, this ingredient gives Choline Force a big advantage, and a few of our testers noticed the difference.
    • L-Phenylalanine – 252 mg
      • L-Phenylanine is an amino acid that promotes general brain function and reduces the effects of age-related memory decline. Some potential side effects of L-phenylalanine supplementation include headaches and jitters. Those with Parkinson’s and schizophrenia can develop other negative symptoms when taking phenylalanine.
    • Ginkgo leaf extract (24% ginkgoflavonglycosides) – 60 mg
      • Ginkgo has been used for thousands of years to promote memory in Chinese medicine. More recently, clinical studies and research reviews have pointed to its efficacy in fighting dementia and neural decline.
    • Other Ingredients: Hydroxypropylmethylcellulose (vegetarian capsule), microcrystalline cellulose, and magnesium stearate.
    Choline Force
    3.9 / 5 Score
    Pros
  • Broad spectrum
  • Transparent formulation
  • Not just choline
  • Stimulant free/li>
  • Cons
  • May be best for vegetarians
  • Four capsule serving
  • Summary
    Choline Force is Bulletproof/Upgraded Self's broad-spectrum nootropic. It's got a range of ingredients centered around choline optimization, but it might not be the best stack for those already eating a diet rich in choline.
    Focus
    Energy
    Memory
    Beginner Friendly

    Usage Guidelines

    • Take 4 capsules up to two times per day with food or as directed by your healthcare professional. Choline Force promotes healthy levels of key neurotransmitters in the brain, boosting clear thinking and sharp memory. Choline Force also contains vinpocetine and ginkgo to support health cerebral blood flow, and B-vitamins to support cognitive energy.
    • People have varying amounts of acetylcholine in their brains, thus requiring varying doses. Having too little acetylcholine can decrease brain function, while too much of it (being “choline dominant”) can cause excessive jaw or muscle tension. If you experience these symptoms, reduce your dose of Bulletproof® Choline Force™.
    • If you are taking other substances that increase your body’s demand for acetylcholine, you will especially benefit from this supplement. We had several BrainWiz testers take between 4 and 8 capsules per day.

    What Our Testers Say

    “Choline Force gave me a light ”˜wave’ of energy. That’s how I’d describe it, a wave. It was really mild, but decidedly noticeable. I appreciate that it is a different energy than that of caffeine, which often gives me jitters even in low dosage. There wasn’t a crash, but there were diminished results the more days in a row I took it.”

    “I didn’t really feel much on this supplement. It could have something to do with the fact that I eat about four eggs every day, which are loaded with choline, does not make me the best candidate for this supplement.”

    “I’ve been taking four capsules in the mornings with my coffee. I did feel slightly more focused, but the feeling is gone by midday, when I take four more capsules to help me get through the afternoon slump.”

    “These definitely help me keep my concentration and focus on the task at hand. The effects were more pronounced in the first couple of days, and then the effects diminished. I tried cycling off for a couple of days, and was able to achieve the same focus effect when I started taking it again.”

    BrainWiz Tips

    • Choline Force contains no caffeine, so it pairs well when you’re already taking in caffeine, like with your morning coffee. The light “wave” of energy our testers felt was also most desirable in the morning.
    • Our testers experienced no negative side effects from this supplement. But as with any supplement or nutritional regimen, you should talk to your doctor or medical professional before use. If you do have excess choline, it can cause jaw or muscle tension, which is why the manufacturer suggests a range of potential sizes. This product also contains phenylalanine, which can cause side effects in some people with preexisting conditions.
    • Take just before eating to take advantage of an active digestive system and promote absorption.
    • Our testers felt diminishing effects after roughly a week of taking Choline Force. After a few days off from the supplement, taking one or more servings (4 pills each) of Choline Force once again produced a desired cognitive boost. We recommend pairing it with caffeine or guarana, and to use it in a “1 week on, 3 days off” pattern in order to keep feeling the effects of the supplement.

    Supplement Summary

    Choline Force is a great caffeine-free nootropic stack, especially for those suffering from a choline deficiency. In addition to a cognitive boost and improved focus, some users feel increased physical energy. Though its perceived effects seem to diminish over time, taking a break from the supplement for a few days seems to be enough time for its effectiveness to return.

    Like other Bulletproof/Upgraded Self products, Choline Force is a very clean, transparent supplement with ingredient dosages clearly listed. Our testers had a generally positive experience with no side-effects. They knew exactly what they were taking, in what dosages, and to what effect. This is definitely NOT a mystery pill.

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    Neurofuse Review: Can You Optimize Your Neurons? https://brainwiz.org/supplement-reviews/neurofuse/ https://brainwiz.org/supplement-reviews/neurofuse/#comments Thu, 20 Aug 2015 21:17:11 +0000 http://brainwiz.org/?p=47 Created by Harvard roommates, Neurofuse’s (click for best price) proprietary blend is a combination of 13 ingredients that have been clinically studied for their abilities to improve memory, focus, and mental performance. Many of the ingredients on the list have some effect on the neurotransmitter acetylcholine, a chemical responsible for a number of cognitive functions. We put Neurofuse […]

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    Created by Harvard roommates, Neurofuse’s (click for best price) proprietary blend is a combination of 13 ingredients that have been clinically studied for their abilities to improve memory, focus, and mental performance. Many of the ingredients on the list have some effect on the neurotransmitter acetylcholine, a chemical responsible for a number of cognitive functions.

    We put Neurofuse to the test. Read below to see what each of our four testers thought about this broad-spectrium nootropic stack in our full Neurofuse review.

    Neurofuse Ingredients

    Neurofuse Ingredients

    The Ingredients

    Neurofuse comes in capsule form. There are 30 two-capsule servings per bottle.

    • Vitamin D3, 667iu
      • Vitamin D3 is a fat-soluble vitamin many Westerners, especially adults, do not get enough of, making it one of our most common vitamin deficiencies. Vitamin D deficiency has been linked to cardiovascular disease, mood disorders, and impaired cognition. This isn’t a massive amount of vitamin D by any means, but it’s a fairly common inclusion in many nootropic stacks and may aid the absorption of other ingredients in Neurofuse.
    • Vitamin B6 (Pyridoxine), 3.3mg
      • Vitamin B6 is a water-soluble essential vitamin involved in the production of neurotransmitters. Studies show that when taken in conjunction with Magnesium, B6 improved school attention in children diagnosed with ADHD. Vitamin B6 may also increase the vividness of dreams and our ability to recall them.
    • Vitamin B12 (Cyanocobalamin), 33.3mcg
      • Vitamin B12 is a water-soluble essential vitamin directly related to brain health, including memory and actual brain mass. A number of studies have noted positive associations between vitamin B12 intake and memory tests.
    • Neurofuse Blend – 903mg
      • There are no listed amounts for each individual component of the proprietary blend, but the ingredients are below.Neurofuse Supplement Review
    • Rhodiola Rosea (3% Rosavins, 2% Salidrosides)
      • Rhodiola Rosea is a herb long used in holistic medicine as an anti-fatigue agent. It’s also linked to an increase in the brain’s ability to handle and process stress. This is a fairly common ingredient in many nootropics, and several of our testers find it effective for them. It’s also been linked to very few, if any, negative side effects in clinical and research studies.
    • Caffeine Anhydrous
      • Caffeine is a stimulant acting on the central nervous system. One of the better-researched mental and physical performance enhancers, caffeine is proven to have acute effects on cognitive function and mood when used in conjunction with L-Theanine. This is a combo naturally present in green tea, which could account for that beverage’s calming effects.
    • L-Theanine
    • Bacopa Monnieri P.E. 20%
      • Bacopa Monnieri is an adaptogenic herb used in Ayurveda as an antidepressant and a cognitive booster. While performing stressful cognitive tests, users taking Bacopa Monnieri experienced reduced stress and lowered cortisol (a stress hormone) levels.
    • DMAE Bitartrate
      • DMAE Bitrate, or Deanol,  is a chemical that’s been used to treat ADHD, improve memory, and boost cognitive function. Deanol is essential to the production of choline, one of the building blocks of the neurotransmitter acetylcholine, which is vital for a number of nervous system activities, including signaling the heart to keep beating.
    • Phosphatidylserine 20%
      • Phosphatidylserine is a phospholipid required to maintain healthy nerve cell membranes. It supports cognitive function and the ability to learn and recall new information.
    • Alpha Lipoic Acid
      • Alpha Lipoic Acid is an antioxidant and anti-inflammatory chemical that has been used to treat memory loss and chronic fatigue syndrome.
    • Choline-Bitartrate
      • Choline-Bitartrate, a vitamin-like chemical, is thought to help enhance the levels of acetylcholine in the brain and body, one of the neurotransmitters involved in learning, and other cognitive processes. Some broad spectrum nootropic stacks include compounds involved in choline production without actually pairing them with a choline source; Neurofuse seems to have avoided that mistake.
    • Vinpocetine
      • Vinpocetine is a chemical derived from the periwinkle plant, possibly linked to increased cerebral blood flow.
    • Huperzine A
      • Huperzine A is a compound derived from Chinese club moss that has been used to improve cognitive performance in patients with Alzheimer’s.
    • Other Ingredients: Brown Rice Flour, Magnesium Stearate, Titanium Dioxide, Gelatin

    Usage Guidelines

    For mental performance: Start with 1-2 capsules per day with food. Work up to 3-4 capsules depending on desired effect and tolerance.

    Note: We had BrainWiz testers take between 1 and 4 capsules per day to test a broad range of dosages.

    What Our Testers Say

    “This supplement was great for me. I took this an hour before heading into the gym  in lieu of my caffeine-containing pre-workout drink, and it was very effective. I had great workouts, and both the energy and sharpened focused lasted well after my workout was over. I started with two capsules and worked my way up to four. That may be a pretty high dosage for simply being productive at work, but I noticed an effect on my workouts, definitely.”

    “Neurofuse gave me a jolt of energy. I started with one pill, and although I felt focused and sharp, I also experienced some slight, very slight, jitteriness. The next time I took it, I didn’t experience the jitters, though I stayed at a pretty low dosage (never more than two capsules, most often just one was enough). I would love to see this product offered without the caffeine, since I did feel like it increased my ability to focus and get through an enormous opposition brief under a tight deadline. I will take Neurofuse again, but like I said, probably one capsule at a time.”

    “I started out taking 1 capsule (I also drink coffee in the morning). It gave me a definite sharpness well into the afternoon during the workday. I worked up to three capsules. I didn’t experience the big energy wave like some of the other BrainWiz testers, but I felt sharp and like I was able to handle stress just a little bit better than normal. This was one of the first nootropic stacks I ever tested, and I keep coming back to it at least once a month.”

    “I started with two capsules and worked my way up to four. I felt focused and energized, for the first four days, but they the effects seemed to diminish a little bit over time. I took 1 day off, and then went back to three then four pills with great results.”

    Neurofuse
    4.7 / 5 Score
    Pros
  • Our top rated
  • Easy to time
  • Fought fatigue
  • Boosted energy
  • Boosted focus
  • Cons
  • Best cycled
  • Summary
    Neurofuse is one of the top-rated, broad-spectrum (i.e. a variety of ingredients, some synergistic, some good on their own) nootropics we've tried. We've found it consistent for lasting energy and focus, though we recommend people start with just one capsule to assess tolerance, as Neurofuse contains caffeine.
    Focus
    Energy
    Memory
    Beginner Friendly

    BrainWiz Tips

    • Neurofuse contains caffeine, and although the amount is not listed, it is enough to cause jitteriness in people with caffeine sensitivity, if taken alongside your morning coffee. Do as the manufacturer says and start slowly.
    • In our review of Neurofuse, our testers preferred taking the nootropic stack in the morning or just after lunch to help fight the afternoon crash.
    • Except for the occasional jitteriness, our testers experienced no negative side effects from this supplement. But as with any supplement or nutritional regimen, you should talk to your doctor or medical professional before use.
    • Take just before eating to take advantage of an active digestive system and promote absorption.

    Neurofuse Summary

    Neurofuse is a broad-spectrium nootropic stack featuring a number of powerful, popular ingredients, including caffeine, in a convenient delivery system. It turned out to be a favorite among our testers, who all felt a cognitive boost.

    In addition to a mental boost, some of our testers feel increased physical energy and stamina; at least one of our testers found it most effective to take pre-workout. Though its perceived effects seemed to diminish very slightly over time, taking a break from the supplement for a day or two seems to be enough time for Neurofuse’s effectiveness to return.

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